Entry Level (10th pct.)
$69,000
0–2 years experience
25th Percentile
$82,000
Below average earner
Median (50th pct.)
$102,000
Typical earner
75th Percentile
$127,000
Above average earner
Top Earner (90th pct.)
$156,000
5+ years experience

Registered Nurse Salary Breakdown — Irvine, CA

The table below shows how Registered Nurse salaries in Irvine distribute across experience levels and pay percentiles in 2026.

PercentileAnnual SalaryMonthlyHourly (est.)Profile
10th$69,000$5,750$33Entry-level, new graduate
25th$82,000$6,833$391–3 years experience
Median$102,000$8,500$49Mid-career professional
75th$127,000$10,583$61Experienced professional
90th$156,000$13,000$75Senior / specialist

Source: U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS), adjusted for Irvine regional cost of living. Data as of 2026.

Visual Salary Distribution

10th pct.
$69,000
25th pct.
$82,000
Median
$102,000
75th pct.
$127,000
90th pct.
$156,000

What Affects Registered Nurse Salaries in Irvine?

  • Experience: Entry-level professionals earn significantly less than their senior counterparts. In Irvine, the gap between the 10th and 90th percentile is $87,000.
  • Industry:Registered Nurses working in high-demand industries such as technology, finance, and healthcare often command salaries above the median.
  • Education & Certifications: Advanced degrees and relevant professional certifications can move your salary into the upper quartile.
  • Company size: Larger organizations typically offer higher compensation packages, including bonuses and equity.
  • Location within Irvine: Employers in downtown/central business districts or tech corridors often pay more than suburban offices.

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